default_cancer_model.h

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#pragma once
#include "disease_definition.h"
#include "gender_table.h"
#include "interfaces.h"
#include "weight_model.h"
 
namespace hgps {
 
class DefaultCancerModel final : public DiseaseModel {
  public:
    DefaultCancerModel() = delete;
 
    DefaultCancerModel(DiseaseDefinition &definition, WeightModel &&classifier,
                       const core::IntegerInterval &age_range);
 
    core::DiseaseGroup group() const noexcept override;
 
    const core::Identifier &disease_type() const noexcept override;
 
    void initialise_disease_status(RuntimeContext &context) override;
 
    void initialise_average_relative_risk(RuntimeContext &context) override;
 
    void update_disease_status(RuntimeContext &context) override;
 
    double get_excess_mortality(const Person &entity) const noexcept override;
 
  private:
    std::reference_wrapper<DiseaseDefinition> definition_;
    WeightModel weight_classifier_;
    DoubleAgeGenderTable average_relative_risk_;
 
    DoubleAgeGenderTable calculate_average_relative_risk(RuntimeContext &context);
    double calculate_combined_relative_risk(const Person &entity, const int &start_time,
                                            const int &time_now) const;
    double calculate_relative_risk_for_diseases(const Person &entity, const int &start_time,
                                                const int &time_now) const;
    double calculate_relative_risk_for_risk_factors(const Person &entity) const;
    double calculate_incidence_probability(const Person &entity, const int &start_time,
                                           const int &time_now) const;
 
    void update_remission_cases(RuntimeContext &context);
    void update_incidence_cases(RuntimeContext &context);
    int calculate_time_since_onset(RuntimeContext &context, const core::Gender &gender) const;
};
} // namespace hgps